{"id":3545,"date":"2021-09-06T17:44:11","date_gmt":"2021-09-06T09:44:11","guid":{"rendered":"http:\/\/www.wrxsz.com\/?p=3545"},"modified":"2021-09-06T16:48:13","modified_gmt":"2021-09-06T08:48:13","slug":"9-6-%e5%b7%a5%e4%bf%a1%e9%83%a8%e4%bb%8e%e6%94%bf%e7%ad%96%e3%80%81%e8%b7%af%e5%be%84%e7%ad%89%e5%a4%9a%e6%96%b9%e9%9d%a2%e5%9b%9e%e5%a4%8d%ef%bc%9a%e5%8f%af%e9%99%8d%e8%a7%a3%e5%a1%91%e6%96%99","status":"publish","type":"post","link":"http:\/\/www.wrxsz.com\/?p=3545","title":{"rendered":"9.6 | \u5de5\u4fe1\u90e8\u4ece\u653f\u7b56\u3001\u8def\u5f84\u7b49\u591a\u65b9\u9762\u56de\u590d\uff1a\u53ef\u964d\u89e3\u5851\u6599\u9886\u57df\u524d\u666f\u826f\u597d\uff1b\u6717\u76db\u63a8\u51fa\u7a7a\u5fc3\u578b\u6750\u6df7\u5408\u6280\u672f\u2026\u2026"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3545\" class=\"elementor elementor-3545\" data-elementor-settings=\"[]\">\n\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-element elementor-element-be03033 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-id=\"be03033\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e34c88b elementor-column elementor-col-100 elementor-top-column\" data-id=\"e34c88b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap  elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11cf4e9 elementor-widget elementor-widget-text-editor\" data-id=\"11cf4e9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\"><div id=\"js_content\" class=\"rich_media_content \"><section data-mpa-template=\"t\"><section data-role=\"paragraph\"><section data-id=\"94100\"><section><section><h3><strong>\u4e00\u3001\u7ecf\u6d4e\u8d44\u8baf<\/strong><\/h3><\/section><\/section><\/section><\/section><\/section><section data-mpa-template=\"t\"><section data-role=\"paragraph\"><section data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"91627\"><section><section><section><section><section><section><p>1.\u7531\u4e8e\u65e5\u672c\u653f\u5c40\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u4fc3\u4f7f\u5f53\u5730\u6295\u8d44\u8005\u51cf\u5c11\u8d2d\u4e70\u6d77\u5916\u98ce\u9669\u8f83\u9ad8\u7684\u8d44\u4ea7\uff0c\u9884\u8ba1\u65e5\u5143\u5c06\u8d70\u5f3a\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u65b0\u9996\u76f8\u7531\u8c01\u51fa\u4efb\u7684\u524d\u666f\uff0c\u53ef\u80fd\u4f1a\u8ba9\u5916\u56fd\u8d44\u91d1\u6709\u66f4\u591a\u7406\u7531\u5c06\u8d44\u91d1\u6c47\u5165\u65e5\u672c\u3002<\/p><\/section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><section data-mpa-template=\"t\"><section data-role=\"paragraph\"><section data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"91627\"><section><section><section><section><\/section><section><section><section data-width=\"100%\"><section data-width=\"100%\"><h3><strong>\u4e8c\u3001\u884c\u4e1a\u8d44\u8baf<\/strong><\/h3><\/section><\/section><\/section><section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><p>1.9\u67086\u65e5\uff0c<span style=\"color: #3366ff;\"><strong>\u6c5f\u82cf\u6781\u6c2a\u6c7d\u8f66\u9500\u552e\u670d\u52a1\u6709\u9650\u516c\u53f8\u6210\u7acb\uff0c\u6cd5\u5b9a\u4ee3\u8868\u4eba\u4e3a\u8d75\u6631\u8f89\uff0c\u6ce8\u518c\u8d44\u672c1000\u4e07\u5143\u4eba\u6c11\u5e01\uff0c<\/strong><\/span>\u7ecf\u8425\u8303\u56f4\u5305\u542b\uff1a\u673a\u52a8\u8f66\u5145\u7535\u9500\u552e\uff1b\u5145\u7535\u6869\u9500\u552e\uff1b\u96c6\u4e2d\u5f0f\u5feb\u901f\u5145\u7535\u7ad9\uff1b\u6c7d\u8f66\u88c5\u9970\u7528\u54c1\u9500\u552e\u7b49\u3002<\/p><p>2.9\u67086\u65e5\uff0c<span style=\"color: #3366ff;\"><strong>\u6234\u59c6\u52d2\u9996\u5e2d\u6267\u884c\u5b98\u8868\u793a\uff0c\u534a\u5bfc\u4f53\u82af\u7247\u9700\u6c42\u98d9\u5347\u610f\u5473\u7740\u52302023\u5e74\uff0c\u6c7d\u8f66\u884c\u4e1a\u53ef\u80fd\u5f88\u96be\u627e\u5230\u8db3\u591f\u7684\u534a\u5bfc\u4f53\u82af\u7247\uff0c\u4e0d\u8fc7\u52302023\u5e74\uff0c\u4f9b\u5e94\u77ed\u7f3a\u7684\u60c5\u51b5\u5e94\u8be5\u4e0d\u4f1a\u90a3\u4e48\u4e25\u91cd\u3002<\/strong><\/span>\u53d7\u5168\u7403\u65b0\u51a0\u75ab\u60c5\u7684\u5f71\u54cd\uff0c\u6c7d\u8f66\u5236\u9020\u5546\u5728\u53bb\u5e74\u88ab\u8feb\u5173\u95ed\u4e86\u5de5\u5382\uff0c\u5728\u82af\u7247\u4ea4\u4ed8\u65b9\u9762\uff0c\u5b83\u4eec\u9762\u4e34\u7740\u5e9e\u5927\u7684\u6d88\u8d39\u7535\u5b50\u884c\u4e1a\u7684\u6fc0\u70c8\u7ade\u4e89\uff0c\u75ab\u60c5\u671f\u95f4\u53d7\u5230\u4e86\u4e00\u7cfb\u5217\u4f9b\u5e94\u94fe\u4e2d\u65ad\u7684\u6253\u51fb\u3002<\/p><p>3.<span style=\"color: #3366ff;\"><strong>\u534e\u4e3a\u8fd1\u65e5\u53d1\u5e03\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848\u4eba\u4e8b\u4efb\u547d\u901a\u77e5\uff0c\u539f\u534e\u4e3a\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848BU\u603b\u88c1\u738b\u519b\u8f6c\u4efbBU COO\uff0c\u5e76\u517c\u4efb\u667a\u80fd\u9a7e\u9a76\u89e3\u51b3\u65b9\u6848\u4ea7\u54c1\u7ebf\u603b\u88c1\u3002<\/strong><\/span>\u4efb\u547d\u663e\u793a\uff0c\u4f59\u627f\u4e1c\u7ee7\u7eed\u62c5\u4efb\u534e\u4e3a\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848BU CEO\uff1b\u738b\u519b\u62c5\u4efb\u534e\u4e3a\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848BU COO\uff0c\u5e76\u517c\u4efb\u667a\u80fd\u9a7e\u9a76\u89e3\u51b3\u65b9\u6848\u4ea7\u54c1\u7ebf\u603b\u88c1\uff1b\u535e\u7ea2\u6797\u4efb\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848BU CTO\u3001\u667a\u80fd\u6c7d\u8f66\u89e3\u51b3\u65b9\u6848BU\u7814\u53d1\u7ba1\u7406\u90e8\u90e8\u957f\u3002\uff08\u65b0\u6d6a\u79d1\u6280\uff09<\/p><p>4.\u8fd1\u65e5\uff0c<span style=\"color: #3366ff;\"><strong>\u56fd\u5bb6\u53d1\u6539\u59d4\u4ea7\u4e1a\u53d1\u5c55\u53f8\u8d1f\u8d23\u540c\u5fd7\u5728\u4eac\u8c03\u7814\u65b0\u80fd\u6e90\u6c7d\u8f66&#8221;\u6362\u7535\u6a21\u5f0f&#8221;\u548c\u5e94\u7528\u60c5\u51b5\u3002\u5728\u8c03\u7814\u4e2d\uff0c\u5b9e\u5730\u67e5\u770b\u4e86\u65b0\u80fd\u6e90\u6c7d\u8f66\u6362\u7535\u7ad9\u548c\u8f66\u8f86\u73b0\u573a\u66f4\u6362\u52a8\u529b\u7535\u6c60\uff0c\u4e0e\u884c\u4e1a\u534f\u4f1a\u3001\u6709\u5173\u4f01\u4e1a\u5c31\u8f66\u7535\u5206\u79bb\u3001\u7535\u6c60\u6807\u51c6\u5316\u3001\u5145\u6362\u7535\u7ed3\u5408\u7b49\u8fdb\u884c\u4e86\u6c9f\u901a\u4ea4\u6d41\u3002<\/strong><\/span>\u636e\u4e86\u89e3\uff0c\u76ee\u524d\u5168\u56fd\u5df2\u6709\u8d85\u8fc7700\u5ea7\u6362\u7535\u7ad9\uff0c\u4e3b\u8981\u5efa\u8bbe\u4e8e\u516c\u5171\u505c\u8f66\u573a\u3001\u77ff\u533a\u3001\u6e2f\u53e3\u7b49\u573a\u6240\uff0c\u4e00\u6b21\u6362\u7535\u65f6\u95f4\u7ea65-10\u5206\u949f\uff0c\u63d0\u9ad8\u4e86\u65b0\u80fd\u6e90\u6c7d\u8f66\u4f7f\u7528\u7684\u4fbf\u5229\u6027\u3002\uff08\u4e2d\u8bc1\u7f51\uff09<\/p><p>5.<strong><span style=\"color: #3366ff;\">\u8fde\u9501\u533b\u7597\u670d\u52a1\u673a\u6784\u201c\u5353\u6b63\u533b\u7597\u201d\u5df2\u5b8c\u62106000\u4e07\u7f8e\u5143E\u8f6e\u878d\u8d44<\/span>\uff0c<\/strong>\u6b64\u8f6e\u878d\u8d44\u7531\u4e00\u5bb6\u56fd\u5185\u79d1\u6280\u4f01\u4e1a\u9886\u6295\uff0c\u4e00\u5bb6\u9999\u6e2f\u5546\u4e1a\u96c6\u56e2\u8ddf\u6295\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u5b8c\u5584\u7ebf\u4e0b\u670d\u52a1\u80fd\u529b\u548c\u63d0\u5347\u7ebf\u4e0a\u670d\u52a1\u80fd\u529b\u548c\u6d41\u7a0b\u534f\u540c\u3002<\/p><p>6<strong>.<span style=\"color: #3366ff;\">9\u67086\u65e5\uff0c\u4e0a\u4ea4\u6240\u5411\u79d1\u5174\u5236\u836f\u4e0b\u53d1\u76d1\u7ba1\u5de5\u4f5c\u51fd\uff0c\u5c31\u516c\u53f8\u76f8\u5173\u4e8b\u9879\u63d0\u51fa\u76d1\u7ba1\u8981\u6c42\u3002<\/span><\/strong><\/p><p>7.<span style=\"color: #3366ff;\"><strong>\u667a\u5eb7\u535a\u836f\u6bcd\u516c\u53f8\u79d1\u8d5b\u777f\u751f\u7269\u5ba3\u5e03\u4e0eAdastra Pharmaceuticals\u8fbe\u6210\u534f\u8bae\uff0c\u83b7\u5f97zotiraciclib\uff08ZTR\/TG02\uff09\u7684\u5168\u7403\u72ec\u5bb6\u6743\u5229\u3002<\/strong><\/span>\u636e\u4ecb\u7ecd\uff0cZTR\u662f\u4e00\u79cd\u53e3\u670d\u9ad8\u6548CDK9\u6291\u5236\u5242\uff0c\u80fd\u591f\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u964d\u89e3Mcl-1\u548cMyc\u81f4\u764c\u86cb\u767d\u3002\u76ee\u524dZTR\u6b63\u88ab\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u9ad8\u7ea7\u522b\u795e\u7ecf\u80f6\u8d28\u7624\u548c\u5f25\u6f2b\u6027\u5185\u6e90\u6027\u8111\u6865\u795e\u7ecf\u80f6\u8d28\u7624\u3002<\/p><p>8.<span style=\"color: #3366ff;\"><strong>\u8fd1\u65e5\uff0cDSP\u82af\u7247\u53ca\u89e3\u51b3\u65b9\u6848\u63d0\u4f9b\u5546\u201c\u4e2d\u79d1\u672c\u539f\u201d\u5ba3\u5e03\u5b8c\u6210\u4ebf\u5143A\u8f6e\u878d\u8d44\uff0c\u7531\u540c\u521b\u4f1f\u4e1a\u548c\u666e\u534e\u8d44\u672c\u8054\u5408\u9886\u6295\uff0c\u6df1\u521b\u6295\u3001\u9ad8\u521b\u6fb3\u6d77\u8ddf\u6295<\/strong>\uff0c<\/span>\u672c\u8f6e\u878d\u8d44\u5c06\u4e3b\u8981\u7528\u4e8e\u65b0\u4e00\u4ee3\u667a\u80fd\u878d\u5408\u578bDSP\u82af\u7247\u7684\u91cf\u4ea7\u53ca\u9ad8\u6027\u80fd\u9886\u57dfDSP\u82af\u7247\u7684\u7814\u53d1\u3002<\/p><section data-mpa-template=\"t\"><section data-role=\"paragraph\"><section data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"91627\"><section data-width=\"100%\"><section><section><section><\/section><section><section><section data-width=\"100%\"><section data-width=\"100%\"><h3><strong>\u4e09\u3001\u5851\u6599\u8d44\u8baf<\/strong><\/h3><\/section><\/section><\/section><section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><\/section><p>1.<strong><span style=\"color: #3366ff;\">\u6717\u76db\u76ee\u524d\u6b63\u5728\u5411\u5e02\u573a\u63a8\u51fa\u5176\u7a7a\u5fc3\u578b\u6750\u6df7\u5408\u6280\u672f\u3002<\/span><\/strong>\u5229\u7528\u8fd9\u4e00\u65b0\u7684\u8f7b\u91cf\u5316\u8bbe\u8ba1\u6280\u672f\uff0c\u53ef\u4ee5\u91c7\u7528\u5851\u6599\u6df7\u5408\u7269\uff0c\u5728\u4f20\u7edf\u6ce8\u5c04\u673a\u4e0a\u5bf9\u91d1\u5c5e\u7a7a\u5fc3\u578b\u6750\u8fdb\u884c\u529f\u80fd\u5316\uff0c\u7531\u6b64\u800c\u83b7\u5f97\u7684\u5851\u6599-\u91d1\u5c5e\u590d\u5408\u6750\u6599\u90e8\u4ef6\uff0c\u76f8\u6bd4\u4ee5\u524d\u91c7\u7528\u5176\u4ed6\u6280\u672f\u529f\u80fd\u5316\u7684\u7a7a\u5fc3\u578b\u6750\u800c\u8a00\uff0c\u62e5\u6709\u66f4\u5927\u7684\u626d\u8f6c\u521a\u5ea6\u548c\u5f3a\u5ea6\u3002<\/p><p>2.\u8fd1\u65e5\uff0c<span style=\"color: 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